Limited data are available regarding optimal management strategies for women with persistent or recurrent BV. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Metronidazole is also available as a cream/gel to be used on the skin, and as tablets/medicine to take by mouth. A glass of water can be taken after administration to aid in swallowing. Treatment of asymptomatic BV among pregnant women at low risk for preterm delivery has not been reported to reduce adverse outcomes of pregnancy in a large multicenter randomized controlled trial (1050). Try searching for what you seek or ask your own question. For details see our conditions. Metronidazole does not inhibit acetaldehyde dehydrogenase, as occurs with disulfiram. Theres one primary culprit, but its not the only possible explanation. Male partner treatment also had an immediate effect on the composition of the penile microbiota; however, this was not as pronounced at day 28, compared with that among women. If you forget to use the gel, use it as soon as you remember. Metronidazole gel 0.75% one full applicator (5 g) intravaginally, once a day for 5 days. With maternal oral therapy, breastfed infants receive metronidazole in doses that are less than those used to treat infections among infants, although the active metabolite adds to the total infant exposure. Some side effects may occur that usually do not need medical attention. So, dont panic just because you see a little bit of it down there. But vaginal dischargecan be alarming, especially if you dont usually experience it. Let your provider know all of the medications you're taking so they can check for interactions with metronidazole vaginal gel. Vandazole and generic metronidazole vaginal gel are both the same strength (0.75%) and typically used every night at bedtime (or sometimes twice a day, if using the generic) for about 5 days. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Gently push on the plunger of the applicator to empty the gel into your vagina. Secnidazole is listed as an alternative regimen, due to its higher cost and lack of long-term outcomes compared with recommended BV treatments. Contact your provider if you experience vaginal irritation after using metronidazole vaginal gel. Metronidazole Side Effects: Capsules, Gel, Alcohol, and More - Healthline Evaluation of short-term valacyclovir suppression among women with HSV-2 did not decrease the risk for BV, despite effective suppression of HSV-2 (995). If youve been treated more than three times in a year for BV, consider wearing condoms with sexual intercourse, Dr. Goje advises. Make sure you use metronidazole vaginal gel exactly as prescribed to you. . In a phase 3 clinical trial of secnidazole 2 g oral granules versus placebo, BV clinical cure rates at days 2130 were 53% in the secnidazole arm compared with 19% in the placebo arm (p<0.001) (1013). If you are being treated for a sexually transmitted disease, avoid sexual contact until you have finished your treatment. Bacterial Vaginosis - STI Treatment Guidelines - CDC Up to 70% of peoplewith this sexually transmitted infection dont notice symptoms.
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