Documentation procedure may differ between treatment centers (documentation form); however, certain items are mandatory for patient safety and legal purposes: (1) patient name and number, (2) date and time of the extravasation, (3) name of the drug extravasated and the diluent used (if applicable), (4) signs and symptoms (also reported by the patient), (5) description of the IV access, (6) extravasation area (and the approximate amount of the drug extravasated), and (7) management steps with time and date. DO NOT flush the line 7. 0000001363 00000 n PDF Intravenous Medication Guidelines for Adults - VCHCA Prompt interdisciplinary action is often necessary for the treatment of extravasation injuries. 0000030204 00000 n Oral administration of diltiazem with propranolol in five normal volunteers resulted in increased propranolol levels in all subjects and bioavailability of propranolol was increased approximately 50%. Elevate the affected extremity Overdosage experience is limited. The prolongation of PR interval correlated significantly with plasma diltiazem concentration in normal volunteers using the Sigmoidal Emax model. Transition to other antiarrhythmic agents following administration of diltiazem hydrochloride injection is generally safe. 0000025152 00000 n %%EOF . The patient should receive the skin graft for recovering her arm skin. (5 mg/mL) Drug classes: Calcium channel blocking agents, Group IV antiarrhythmics. Calcinosis cutis: Management - UpToDate Physical Incompatibilities: Because of potential physical incompatibilities, it is recommended that diltiazem hydrochloride injection not be mixed with any other drugs in the same container. You may opt-out of email communications at any time by clicking on The staff involved in the infusion and management of cytotoxic drugs must be trained to implement several preventive protocols for the minimization of the risk of extravasation. Cardizem and Injection site extravasation - a phase IV clinical study Dilution: To prepare diltiazem hydrochloride injection for continuous intravenous infusion, aseptically transfer the appropriate quantity (see chart) of diltiazem hydrochloride injection to the desired volume of either Normal Saline, D5W, or D5W/0.45% NaCl.
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